Are Antiplatelet Agents Beneficial in Prevention of Infective Endocarditis?—Reply
نویسندگان
چکیده
منابع مشابه
Antiplatelet agents in stroke prevention
In primary prevention, aspirin reduces the risk of stroke but not of myocardial infarction in women while in men only the risk of myocardial infarction but not stroke could be significantly reduced. Only aspirin has been shown to be safe and effective in large randomized trials in the first 48 hours after ischemic stroke. Aspirin/dipyridamole and clopidogrel both reduce the risk of a combined c...
متن کاملAntiplatelet agents in stroke prevention.
In primary prevention, aspirin reduces the risk of stroke but not of myocardial infarction in women while in men only the risk of myocardial infarction but not stroke could be significantly reduced. Only aspirin has been shown to be safe and effective in large randomized trials in the first 48 hours after ischemic stroke. Aspirin/dipyridamole and clopidogrel both reduce the risk of a combined c...
متن کاملProphylaxis of experimental endocarditis with antiplatelet and antithrombin agents: a role for long-term prevention of infective endocarditis in humans?
BACKGROUND Infective endocarditis (IE) mostly occurs after spontaneous low-grade bacteremia. Thus, IE cannot be prevented by circumstantial antibiotic prophylaxis. Platelet activation following bacterial-fibrinogen interaction or thrombin-mediated fibrinogen-fibrin polymerization is a critical step in vegetation formation. We tested the efficacy of antiplatelet and antithrombin to prevent exper...
متن کاملVascular dementia: potential of antiplatelet agents in prevention.
The term 'vascular dementia' (VaD) corresponds to a clinicoradiological syndrome that can be defined with more or less restriction. VaD can result from: (1) cortical or subcortical ischemic lesions related to the occlusion of large vessels, (2) lacunar infarcts with or without white-matter lesions at the subcortical level related to small-vessel diseases, (3) ischemic lesions related to hypoper...
متن کاملAntiplatelet agents in secondary prevention of stroke: a perspective.
BACKGROUND AND PURPOSE Antiplatelet agents are widely used in the secondary prevention of stroke and other vascular events. The purpose of this review is to give a perspective of the factors involved in clinical practice for selecting antiplatelet drugs appropriate to the patient population. SUMMARY OF REVIEW Aspirin remains the most popular drug, because it is modestly effective (approximate...
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ژورنال
عنوان ژورنال: JAMA Cardiology
سال: 2019
ISSN: 2380-6583
DOI: 10.1001/jamacardio.2019.3089